Simparica Trio for Large Dogs (44.1 - 88 lbs)

Simparica Trio for Large Dogs is a fast-acting, monthly chewable tablet that delivers complete parasite protection – no vet visit or prescription required. This triple-action formula defends your dog against fleas, ticks, heartworm disease, roundworms, and hookworms with a single, tasty chew.

Ideal for dogs weighing 44.1–88 lbs, Simparica Trio uses powerful, vet-trusted ingredients: sarolaner, moxidectin, and pyrantel. It kills fleas before they lay eggs, eliminates five species of ticks, and prevents heartworm with every dose.

Whether for monthly prevention or year-round protection, this chewable makes parasite control simple — with no vet prescription needed.

Key Benefits:

• No Vet RX Required – Buy online with no prescription needed.
• Triple Protection – Fights fleas, ticks, and internal worms.
• Fast & Reliable – Kills fleas fast and prevents heartworm.
• Easy Monthly Chew – Dogs love the taste.
• Trusted Ingredients – Vet-quality formula with sarolaner, moxidectin & pyrantel.

Perfect For:

• Dogs weighing 44.1–88 lbs (20.1–40 kg)
• Pet parents looking for all-in-one parasite protection
• Those wanting no vet prescription hassle

Ideal For:

• Large dogs weighing 88.1–132 lbs (40.1–60 kg)
• Dog owners looking for broad parasite coverage with no vet visit
• Year-round flea, tick, and worm prevention in one dose

How to Use Simparica Trio

• Give 1 chew every 30 days.
• Treat on the same date each month.
• Can be given as a treat, with food, or directly by mouth.
• Start at minimum of 8 weeks of age & 2.8 lbs (1.25 kg) body weight.
• If a dose is missed, give it as soon as remembered and continue monthly.
• Do not split chews.
• Dogs over 60 kg (132 lbs) require the correct combo of chews.

Important: Regional Packaging

Simparica Trio packaging may look different from our region.
This is purely cosmetic.
No matter the box, the ingredients, dosage, and quality are exactly the same. Rest assured, you're getting the same trusted protection worldwide.