Collection: Simparica Trio

Simparica Trio is one of the most powerful all-in-one parasite treatments for dogs — protecting against fleas, ticks, heartworm, roundworm, and hookworm with a single monthly chew. Many U.S. dog owners choose to buy Simparica Trio online because it’s fast-acting, broad-spectrum, and easier than juggling multiple medications.

In many countries, Simparica Trio is sold without a vet prescription, which is why international veterinary pharmacies like us can supply the exact same Zoetis-manufactured product directly to American customers. The formula, packaging, batch numbers, and safety profile are identical to what U.S. veterinarians dispense.

Simparica Trio starts killing fleas within 3 hours and eliminates ticks within 8 hours, preventing re-infestation and breaking the flea life cycle in the home. Its active ingredients — Sarolaner, Moxidectin, and Pyrantel — work together to provide complete parasite protection for 35 days when used monthly and dosed correctly for your dog’s weight range.

When ordering Simparica Trio online, choose the weight bracket equal to or above your dog’s current weight, and ensure monthly dosing for consistent protection. Puppies can start Simparica Trio from 8 weeks of age as long as they weigh at least 2.8 lbs.

Shipping times vary depending on carrier processing, but most U.S. customers receive their order within 7–15 business days. Products arrive sealed, factory-fresh, and sourced from licensed veterinary distributors overseas.

For dogs with allergies, neurological conditions, or a history of seizures, consult your veterinarian before use — even though the product is safe for most healthy dogs. Follow label dosing instructions and avoid mixing Simparica Trio with other parasite treatments unless directed by a vet.

This collection includes all strength ranges of Simparica Trio for dogs, including 3-pack and 6-pack options for long-term protection.