Simparica Trio for Medium Dogs (22.1 - 44 lbs)

Simparica Trio for Medium Dogs is a powerful monthly chewable that delivers triple protection against fleas, ticks, and worms — all without a vet visit or prescription. This easy-to-give tablet is packed with trusted active ingredients: sarolaner, moxidectin, and pyrantel, providing comprehensive defense against fleas, ticks, heartworms, hookworms, and roundworms.

Designed for dogs weighing 22.1–44 lbs, Simparica Trio acts quickly — killing fleas before they can reproduce, eliminating five tick species, and preventing deadly heartworm disease.

With no prescription (no vet script) required, this vet-grade treatment is perfect for convenient at-home parasite control.

Key Benefits:

• No RX Required: Skip the vet – order online with no prescription.
• Broad-Spectrum Protection: Targets fleas, ticks, heartworms, hookworms, and roundworms.
• Fast-Acting: Starts working within hours of dosing.
• Tasty Monthly Chew: Palatable and easy to administer.
• Vet-Grade Ingredients: Trusted formula used by veterinarians.

Perfect For:

• Dogs weighing 22.1–44 lbs (10.1–20 kg)
• Pet owners seeking no prescription flea & worm protection
• Year-round parasite defense in a single monthly dose

How to Use Simparica Trio

• Give 1 chew every 30 days.
• Treat on the same date each month.
• Can be given as a treat, with food, or directly by mouth.
• Start at minimum of 8 weeks of age & 2.8 lbs (1.25 kg) body weight.
• If a dose is missed, give it as soon as remembered and continue monthly.
• Do not split chews.
• Dogs over 60 kg (132 lbs) require the correct combo of chews.