Simparica Trio for Medium Dogs (22.1 - 44 lbs)

Simparica Trio for Medium Dogs is a powerful monthly chewable that delivers triple protection against fleas, ticks, and worms — all without a vet visit or prescription. This easy-to-give tablet is packed with trusted active ingredients: sarolaner, moxidectin, and pyrantel, providing comprehensive defense against fleas, ticks, heartworms, hookworms, and roundworms.

Designed for dogs weighing 22.1–44 lbs, Simparica Trio acts quickly — killing fleas before they can reproduce, eliminating five tick species, and preventing deadly heartworm disease.

With no prescription (no vet script) required, this vet-grade treatment is perfect for convenient at-home parasite control.

Key Benefits:

• No RX Required: Skip the vet – order online with no prescription.
• Broad-Spectrum Protection: Targets fleas, ticks, heartworms, hookworms, and roundworms.
• Fast-Acting: Starts working within hours of dosing.
• Tasty Monthly Chew: Palatable and easy to administer.
• Vet-Grade Ingredients: Trusted formula used by veterinarians.

Perfect For:

• Dogs weighing 22.1–44 lbs (10.1–20 kg)
• Pet owners seeking no prescription flea & worm protection
• Year-round parasite defense in a single monthly dose

How to Use Simparica Trio

• Give 1 chew every 30 days.
• Treat on the same date each month.
• Can be given as a treat, with food, or directly by mouth.
• Start at minimum of 8 weeks of age & 2.8 lbs (1.25 kg) body weight.
• If a dose is missed, give it as soon as remembered and continue monthly.
• Do not split chews.
• Dogs over 60 kg (132 lbs) require the correct combo of chews.

Important: Regional Packaging

Simparica Trio packaging may look different from our region.
This is purely cosmetic.
No matter the box, the ingredients, dosage, and quality are exactly the same. Rest assured, you're getting the same trusted protection worldwide.